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Particle classification

Classizer One from EOS

CLASSIZER™ ONE is the cutting-edge analysis platform for particles in mixture or monodisperse samples in the range of 0.1 – 20 μm. It does an optical classification, gives absolute particle size distribution, and numerical concentration of each single particle populations irrespectively of polydispersity & composition. Quality control of optical particle structures as porosity, wetting, aspect ratio, payload, impurities, and measurement of the particle behavior and the particle formulation stability directly in real heterogeneous non-filtered target biological, industrial, or environmental fluids is possible.

Features

Measurements of mono- and polydisperse samples in various liquids
High-resolution continuous flow analysis
Optical classification, absolute particle size distribution and numerical concentration
Characterization of agglomeration and impurities
Patented methode
Measurement range 0.1 – 20 μm

Further information

Classizer One is based on the patented Single Particle Extinction and Scattering (SPES) method.

SPES takes advantage of a self-reference interferometric measurement of the scattered wavefront in the forward direction by a single illuminated particle. Particles are driven by a laminar fluid flow through the waist region of a focused laser beam causing an interference pattern. A robust pulse shape validation scheme creates the unique EOS CLOUDS: a 2D histogram which is the optical fingerprint of the sample. Heterogeneous samples produce simultaneously different clouds for each particle population, which can be individually selected, analysed, and compared.

Classizer One provides optical classification, absolute particle size distribution, and numerical concentration of each single particle populations irrespectively of polydispersity & composition. Classizer One is used for quality control of optical particle structures as porosity, wetting, aspect ratio, payload, impurities, and shelf-life, without intermediate steps (e.g., purification/filtration).