Scanner de criblage cellulaire à haut débit
Cell³iMager Neo de SCREENLes Cell3iMagers de SCREEN sont des scanners à champ lumineux conçus spécifiquement pour simplifier et accélérer la mesure quantitative et qualitative des sphéroïdes 3D. Ce système d'imagerie unique basé sur des LED permet à l'utilisateur d'identifier et de mesurer rapidement et automatiquement un ou plusieurs sphéroïdes par puits dans une microplaque. Le logiciel d'analyse 3D optimisé qui l'accompagne permet d'accélérer la capture d'images, la mesure et l'analyse des données, et est compatible avec les principales plateformes de culture cellulaire 3D. Pour s'adapter aux différents budgets et aux besoins de débit, l'imageur est disponible en deux modèles : le Cell3iMager Neo (cc-3000) à plaque unique ou le Cell3iMager (cc-5000) à quatre plaques.
- Système d'imagerie à base de LED
- Temps de balayage rapide jusqu'à 30 × plaques de 384 puits/heure
- Définitions de plaques prédéfinies pour toutes les principales plateformes de culture cellulaire
- Logiciel complet d'analyse d'images 2D et 3D
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High-resolution spheroid scanning meets high-throughput demands
Imaging spheroids using conventional or even automated microscopes is a slow, low throughput process. High content imaging systems overcome some of these throughput issues, but are comparatively expensive, and still suffer from slow image capture/processing, and image analysis software not optimized for 3D spheroids. The Cell3iMager overcomes these limitations, featuring high-resolution scanning (up to 9600 dpi) without compromising scan time. This minimizes 'out of incubator' time to avoid jeopardizing cell health during analysis. The powerful automated measurement and analysis software eliminates cumbersome manual morphological measurements and improves data reproducibility. Simply scan, measure, and analyze.
Label-free detection enables faster processing with fewer processes
Although adaptable to higher throughput plate readers, biochemical assays that monitor viability (e.g., ATP content) can effectively correlate to spheroid size, but are often lytic or otherwise destructive in nature, requiring multiple replicates to be run for longitudinal studies. Label-free measurement of changes in 3D microtissue size and morphology using the Cell3iMager enables efficient assessment of phenotypic endpoints without disrupting microtissue growth, and can be used to focus selection of therapeutic targets and treatment strategies before costly and tedious testing in animal models.
Powerful 3D software handles routine and complex workflows
Fast, high-resolution bright field optics and image capture are only half of the Cell3iMager package. Scanning more plates faster means more data to analyze, and the Cell3iMager’s intelligent software provides the power needed to keep up. The software reports key spheroid growth and morphological parameters, including spheroid number, size, shape, and growth kinetics over time. Basic scanning setup parameters are included, and intelligent object identification settings can be customized and saved for repeated use to ensure accuracy and reproducibility within and between experiments. Growth curves and histograms are generated and can be copy/pasted directly, or raw data can be exported as CSV files for import into statistical and graphing software.
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Quantum Design S.A.R.L.
1 avenue de l’Atlantique
Bâtiment Mac Kinley
91940 Les Ulis
France
| Tél. : | 01 69 19 49 49 |
| Fax : | 01 69 19 49 30 |
| Email : | france@qd-europe.com |
