Particle classification

Classizer One from EOS

CLASSIZER™ ONE is the cutting-edge analysis platform for particles in mixture or monodisperse samples in the range of 0.1 – 20 μm. It does an optical classification, gives absolute particle size distribution, and numerical concentration of each single particle populations irrespectively of polydispersity & composition. Quality control of optical particle structures as porosity, wetting, aspect ratio, payload, impurities, and measurement of the particle behavior and the particle formulation stability directly in real heterogeneous non-filtered target biological, industrial, or environmental fluids is possible.

Features
  • Measurements of mono- and polydisperse samples in various liquids
  • High-resolution continuous flow analysis
  • Optical classification, absolute particle size distribution and numerical concentration
  • Characterization of agglomeration and impurities
  • Patented methode
  • Measurement range 0.1 – 20 μm

Further information

Classizer One is based on the patented Single Particle Extinction and Scattering (SPES) method.

SPES takes advantage of a self-reference interferometric measurement of the scattered wavefront in the forward direction by a single illuminated particle. Particles are driven by a laminar fluid flow through the waist region of a focused laser beam causing an interference pattern. A robust pulse shape validation scheme creates the unique EOS CLOUDS: a 2D histogram which is the optical fingerprint of the sample. Heterogeneous samples produce simultaneously different clouds for each particle population, which can be individually selected, analysed, and compared.

Classizer One provides optical classification, absolute particle size distribution, and numerical concentration of each single particle populations irrespectively of polydispersity & composition. Classizer One is used for quality control of optical particle structures as porosity, wetting, aspect ratio, payload, impurities, and shelf-life, without intermediate steps (e.g., purification/filtration).

Applications

R&D in formulations
Heterogeneous samples
Process Quality Control and PCA
Impurities identification
Life sciences
Environmental science

Downloads

Datasheets

CLASSIZER ONE

Application Notes

Addressing the issue of wetting and clustering
Analysis of polymeric particles
Batch to batch consistency via multiparametric SPES
Continuous SPES flow analysis
Multiparametric classification of particles
Quantitative classification in biological liquids

Contact

Julien Dumouchel
Julien Dumouchel

Contact

Quantum Design AG

Route du Roule 41
CH-1723 Marly
Switzerland

Phone:+41 21 8699-033
E-Mail:suisse@qd-europe.com
Julien DumouchelSales Manager
+41 21 8699033
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