Surface Plasmon Resonance microscopy (SPRm) system
SPRm 200 from Biosensing InstrumentThe SPRm 200 system integrates optical microscopy and SPR and is a powerful technique for measuring binding activities of membrane proteins in vitro. It allows the simultaneous measurement of phenotypical changes of the sample via bright-field microscopy and binding kinetics via SPR.
- In vitro SPR measurements on cellular cultures
- Integrates bright-field optical microscopy to SPR
- In vitro label-free mapping of binding activities
- Nanometer scaled binding response of virus, bacteria and nanoparticles
- Physiological ambient measurements
Further information
The SPRm 200 system opens a new frontier in the study of molecular interactions by integrating optical microscopy with Surface Plasmon Resonance technology. Designed especially for in-vitro and label-free measurement of binding activity and cell kinetics, SPRm 200 provides a spatial visualization of cellular structures together with local binding activities. Real-time interactions of the drug and membrane proteins can be measured in their native state without needing to extract proteins from the cell. With its outstanding sensitivity and stability, SPRm 200 also measures binding activities of bacteria and virus interactions and enables the development of new methods for nanoparticle drug delivery.
Key features:
Integrated optical microscopy with bright-field and SPR in one instrument. Large field of view with high resolution optics (1 µm) to visualize single or multiple cells.
In vitro label-free binding activities mapping provides SPR sensorgrams and binding activity map of individual cells, as well as the binding kinetic constants (ka, kd, KD).
Nanometer scaled binding response study of virus, bacteria and nanoparticles for drug delivery designs.
Suitable for:
- Label-free molecular binding measurement of in vitro cell membrane proteins
- Quantitative mapping of binding affinity and kinetics in real time
- Simultaneous optical imaging with SPR measurements
- Direct drug interaction studies of single and/or multiple cells
- Nanoscale monitoring of viruses and bacteria binding events
Specifications
Applications
- Integrated optical microscopy
- In vitro and label-free binding activities mapping
- Nanometer scaled binding response study
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Quantum Design s.r.l.
Via Francesco Sapori, 27
00143 Roma
Italy
| Phone: | +39 06 5004204 |
| Fax: | +39 06 5010389 |
| E-mail: | italy@qd-europe.com |
